Sam Gross (b. August 7, 1933) is an American gag cartoonist.
Born in Bronx, New York City, Gross began cartooning in 1962. His cartoons have appeared in numerous magazines, including Cosmopolitan, Esquire, Good Housekeeping, Harvard Business Review and The New Yorker. He was cartoon editor for National Lampoon and Parents Magazine.
Gross created the comic strip Cigarman.